Pathogen surveillance and outbreak analysis are critical to preventing and controlling disease outbreaks and re-emergence. A significant challenge in source tracing outbreaks is the ability to genotype pathogens at sufficient resolution to unravel the chain of transmissions. Accurate detection of antimicrobial resistance (AMR) mechanisms is essential for administering correct and efficient treatment regimens and for monitoring multi-drug resistance.
Next-generation sequencing (NGS) of whole pathogen genomes permits transmission analysis with high discriminatory power. An additional benefit of whole genome sequencing (WGS) is its ability to simultaneously provide information on antimicrobial resistance mechanisms present in the microbe.
QIAGEN CLC Genomics ProSuite software, including QIAGEN CLC Genomics Workbench and QIAGEN CLC Microbial Genomics Module, gives you the power to perform accurate outbreak tracing via WGS, and detect AMR mechanisms.
Download the white paper to learn how QIAGEN scientists performed high-resolution outbreak tracing and improved AMR detection in the case of a TB outbreak.